Always check for the MHRA logo and a UK pharmacy license.
Sildenafil is a medicine used to treat erection problems (erectile dysfunction) in men by increasing blood flow. One tablet taken orally with water, usually one hour before sexual activity. Common side effects include headaches, flushing and dizziness. People with heart problems or taking nitrates should avoid Sildenafil due to potential problems. Seek immediate medical attention for prolonged erections or sudden vision / hearing loss.
Tadalafil is used to treat erectile dysfunction (ED) in men by increasing blood flow to the penis during sexual stimulation. Taken daily and orally with water around 30 minutes before sexual activity and lasts up to 36 hours. Common side effects include headaches and muscle aches. What is the main cause of ED? Erectile dysfunction can be caused by psychological factors, medical conditions and/or certain medications.
In younger men with variable or situational ED, stress and anxiety can restrict blood flow to the penis at exactly the wrong moment. In men with ED that doesn’t vary with different partners or different situations, underlying problems with nerves, blood vessels or hormone production may be present. Our clinical team can help you to identify the erectile dysfunction cause and help treat your ED. Erectile dysfunction is the inability to get or keep an erection during sexual activity. This happens when the penile erection chambers fail to generate and maintain the high pressures that characterise a hard erection. Yes: Viagra Connect (sildenafil 50 mg) is available OTC in the UK, after a pharmacist consultation. Other “natural” supplements lack strong clinical evidence. Sildenafil takes effect in 30–60 minutes, but a safe consultation with a pharmacist or doctor is advised. Yes, for Viagra Connect at pharmacies, but a brief pharmacist interview is required.
Prof.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Generic | 10mg | 20 Pills | 48.23€ 45.93€ | |
| Cialis Generic | 60mg | 20 Pills | 65.61€ 62.49€ | |
| Cialis Generic | 20mg | 60 + 6 Pills | 117.76€ 112.15€ | |
| Cialis Generic | 40mg | 30 + 4 Pills | 74.97€ 71.40€ | |
| Cialis Generic | 2.5mg | 360 + 10 Pills | 260.03€ 247.65€ | |
| Cialis Generic | 5mg | 60 + 4 Pills | 86.02€ 81.92€ | |
| Cialis Generic | 2.5mg | 60 + 4 Pills | 83.43€ 79.46€ | |
| Cialis Generic | 60mg | 90 + 6 Pills | 196.67€ 187.30€ | |
| Cialis Generic | 2.5mg | 20 Pills | 40.73€ 38.79€ | |
| Tadalista Super Active | 20mg | 60 + 8 Pills | 230.32€ 219.35€ | |
| Cialis Generic | 20mg | 90 + 6 Pills | 154.71€ 147.34€ | |
| Cialis Generic | 60mg | 270 + 10 Pills | 443.96€ 422.82€ | |
| Cialis Generic | 2.5mg | 30 + 4 Pills | 51.95€ 49.48€ |
Castiglione emphasizes the importance of addressing ED with caution and medical oversight. PDE5 inhibitors like sildenafil and tadalafil must not be taken with nitrate-based heart medications, as this can cause dangerously low blood pressure, fainting, or cardiovascular shock. Always inform your doctor or pharmacist of all medications you’re taking, including supplements.
Usually, sexual stimulation is enough to get things going, but men with ED have trouble staying firm through ejaculation. Lots of things can contribute, like age, high blood pressure, vascular disease, disease, stress, and more. Sexual arousal triggers a response in your body that then triggers nitric oxide production, which relaxes the blood vessels and smooth muscle in the penis. This lets blood rush into the penis, which gets hard as a result. There is an enzyme in the penis called phosphodiesterase that shuts this process off when sex is over.
ED medications work by blocking PDE5 and preventing this shut off. That keeps your erection going longer and stronger. Erectile dysfunction is typically self-diagnosed from the obvious symptoms of struggling to maintain a satisfactory erection. Although ED can be self-diagnosed, it’s recommended that new symptoms should always be discussed with your GP. If you do not wish to contact your GP, a consultation regarding any new symptoms with our clinical team is advised.
Please note, ED can be a sign of underlying health conditions, such as circulatory or heart problems, that should be addressed immediately as they could lead to further and more severe health complications. How can I improve my erectile dysfunction? The best way to improve your erectile function is to take a holistic approach. ED medications work best in the long-term when combined with positive lifestyle changes that promote overall health. Eating a heart-healthy diet, exercising, and avoiding health-harming behaviours like cigarette smoking can make a big difference. Even when taken correctly, ED meds can cause temporary side effects: headache and dizziness facial flushing and warmth indigestion or acid reflux nasal congestion or dryness Rarely, visual disturbances or tinnitus may occur.
In this article by Prof. Fabio Castiglione, we’ll explore the legally available options in the UK, costs, MHRA regulations, the differences between physical and online pharmacies, and possible non-pharmacological alternatives. In the UK, the only ED drug available OTC (over the counter) in pharmacies is sildenafil 50 mg, sold as Viagra Connect. To purchase it, a brief consultation with the pharmacist is required, who will assess your suitability. All other PDE5 inhibitors (tadalafil, vardenafil) remain prescription-only medications (POM).
Average pharmacy price: £10–£15 per tablet Contraindications: use of nitrates, severe hypotension, advanced liver failure The MHRA (Medicines and Healthcare products Regulatory Agency) oversees OTC drug sales. Check for serious heart disease or uncontrolled hypertension. Ensure the patient isn’t taking nitrates or drugs with dangerous interactions. Inform the patient about potential side effects and correct usage. This process acts as a basic medical screening before purchase. If symptoms persist or worsen, stop the medication and consult a specialist immediately. Prof. Castiglione warns against online “miracle pills,” often counterfeit or containing industrial chemicals, thalidomide, or undeclared PDE5 doses.
Use only MHRA-approved pharmacies or trusted platforms like Superdrug Online Doctor.
If your erectile dysfunction has a psychological cause, therapy can provide useful, practical tools that help in the moment, and may help you to deal with the root cause of anxiety or depression. If you frequently experience ED after drinking alcohol, the alcohol may be the cause of your erectile dysfunction. Try having sex without alcohol to see if that helps. Do I still need to complete a questionnaire? As your health can vary over time, we like to check in with all new and returning patients to ensure that there are no new underlying health concerns that may cause issues with a treatment.
Choosing Morrisons Clinic means you’re in control of your healthcare. No more dreaded busy tone or long waiting lists – we’ve got you covered. To make sure you can safely take your preferred treatment, complete our questionnaire which takes approx 3 mins. Our prescribing pharmacists review and individually assess your treatment suitability using their extensive knowledge and clinical experience. Once approved and dispensed, we’ll securely deliver your treatment using our free RoyalMail Tracked 24 option.
Once approved and dispensed, we’ll securely deliver your treatment using our free Royal Mail Tracked 24 option. Our expert prescribing pharmacists are specially trained to review, consult and provide medications online. Our services are delivered by a team of dedicated pharmacists, prescribers and clinicians. Erectile dysfunction (ED) affects up to one in five men during their lifetime and can stem from vascular, neurological, hormonal, or psychological causes. In recent years, interest in over-the-counter meds for erectile dysfunction has surged, drawing attention to non-prescription products, online alternatives, and the risks of uncontrolled use. a cardiology check-up to rule out ischemia or arrhythmias blood pressure and metabolic panel (glucose, cholesterol) a GP visit to evaluate systemic tadalafil 20mg price conditions (diabetes, hypertension, vascular issues) a cardiology check-up to rule out ischemia or arrhythmias blood pressure and metabolic panel (glucose, cholesterol) a GP visit to evaluate systemic conditions (diabetes, hypertension, vascular issues) Only after these exams does Prof.
| Tip | Explanation | Source |
|---|---|---|
| Check for authentic products | Only buy from reputable sources | NHS, MHRA notices |
| Be aware of side effects | Common and severe side effects, report if occurs | MHRA, BNF |
| Avoid alcohol and certain drugs | Can increase side effects or reduce efficacy | NHS, Pharmacist |
| Consult a healthcare professional before use | Especially if having existing health conditions | NHS, General Practitioners |
Castiglione develop the safest and most appropriate treatment, ranging from OTC drugs to his Fabio Regenerative Protocol (PRP + P-Shocks + shockwave).
This integrated approach ensures efficacy, safety, and constant monitoring, reducing the risks of self-medication.
Many men turn to “natural” remedies like L-arginine, ginseng, or yohimbine. Formulas often contain undeclared doses of PDE5 inhibitors.
| Parameter | Value | Comments |
|---|---|---|
| Onset of Action | 30-60 minutes | Varies by individual |
| Duration of Effect | Up to 36 hours | Longer than other ED meds |
| Half-life | 17.5 hours | Affects dosing frequency |
| Food Interaction | Less affected by food intake | Less sensitive than sildenafil |
They can cause unexpected interactions or side effects. The NHS offers ED medications via GP prescription following a confirmed diagnosis. NHS prescription cost: £9 (if not exempt).
Pros: immediate pharmacist assessment, MHRA-approved product. Cons: slightly higher price; requires in-person visit. Services like Superdrug Online Doctor or Boots Online offer a virtual consultation, which, if approved, results in medication delivery. Cons: delivery time, risk of unlicensed websites. Warning: avoid sites offering “meds without prescription” at bargain prices: they often sell counterfeit or dangerous products. Waiting times vary: from same-day to several weeks, based on clinical priority. For faster access and advanced regenerative treatments (PRP + P-Shocks + shockwave), Prof. Fabio Castiglione offers a complete private alternative at the London Erectile Dysfunction Clinic. Prof. Fabio Castiglione is a Consultant Urologist & Andrologist at King’s College Hospital in London, with international training in Europe and the U.S. His experience ranges from advanced surgical techniques to cutting-edge regenerative therapies, with a special focus on erectile dysfunction (ED) and Peyronie’s disease. At his private London clinic, Prof. Castiglione adopts a personalized care model: each patient undergoes a thorough evaluation, including detailed history, 3D penile ultrasound, and vascular or hormonal tests if needed. Based on these findings, the treatment may include standard PDE5 inhibitors (sildenafil, tadalafil), OTC options when suitable, or the Fabio Protocol, a regenerative approach combining: PRP (Platelet-Rich Plasma) to stimulate tissue regeneration via growth factors from the patient’s own blood; P-Shocks, low-intensity focused shockwaves to reduce fibrosis and pain; Radial shockwaves, to boost neovascularization and lymphatic drainage. This protocol, unique in Europe, is ideal for those who don’t respond to traditional meds or want a long-term solution without systemic side effects.